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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KSR2
All Species:
13.64
Human Site:
S539
Identified Species:
30
UniProt:
Q6VAB6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VAB6
NP_775869.3
950
107632
S539
P
A
P
P
L
P
P
S
A
T
P
P
S
P
L
Chimpanzee
Pan troglodytes
XP_001145739
986
111275
S515
P
A
P
P
L
P
P
S
A
T
P
P
S
P
L
Rhesus Macaque
Macaca mulatta
XP_001083311
805
90894
V447
T
P
T
R
A
P
Q
V
I
L
H
P
V
T
S
Dog
Lupus familis
XP_853953
898
99758
L517
K
I
K
C
S
F
V
L
E
P
V
L
K
C
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVC0
959
108554
S549
P
A
P
P
L
P
P
S
A
T
P
P
S
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514916
259
29171
Chicken
Gallus gallus
Q04982
806
89347
G448
T
P
P
A
S
L
P
G
S
L
T
N
V
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137513
942
106704
S530
P
A
P
P
L
P
P
S
A
T
P
P
S
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11346
782
88616
H424
L
P
H
P
C
T
D
H
S
N
S
T
Q
A
S
Honey Bee
Apis mellifera
XP_393005
895
100160
P497
N
S
S
T
P
S
S
P
A
L
L
P
A
N
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05609
821
90288
F463
S
Q
S
L
N
L
V
F
D
P
A
S
D
D
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
84.3
51
N.A.
95.5
N.A.
N.A.
25.1
24.3
N.A.
82.3
N.A.
24.9
36.4
N.A.
N.A.
Protein Similarity:
100
92.1
84.5
64.6
N.A.
97
N.A.
N.A.
26.3
40.2
N.A.
90.1
N.A.
40.9
53.5
N.A.
N.A.
P-Site Identity:
100
100
13.3
0
N.A.
100
N.A.
N.A.
0
13.3
N.A.
100
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
13.3
0
N.A.
100
N.A.
N.A.
0
20
N.A.
100
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
10
10
0
0
0
46
0
10
0
10
10
10
% A
% Cys:
0
0
0
10
10
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% K
% Leu:
10
0
0
10
37
19
0
10
0
28
10
10
0
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
10
0
0
0
0
10
0
10
0
10
0
% N
% Pro:
37
28
46
46
10
46
46
10
0
19
37
55
0
37
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
19
0
19
10
10
37
19
0
10
10
37
0
19
% S
% Thr:
19
0
10
10
0
10
0
0
0
37
10
10
0
10
10
% T
% Val:
0
0
0
0
0
0
19
10
0
0
10
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _